Peptides, hormones, and longevity compounds, delivered across South Dakota.
Licensed providers review your intake online, prescribe the protocol that fits your goals, and ship compounded medication to your door — anywhere from Sioux Falls to Pierre. No clinic visits.
- Online intake reviewed by providers licensed in South Dakota
- 503A/B compounding pharmacies, no gray-market sources
- Shipped to your door — refills auto-renew monthly
$161+/month
Free shipping + free doctor review, no hidden fees
2 minutes · No charge until a South Dakota-licensed provider approves your protocol
LegitScript Certified
Licensed providers in your state
503A/B pharmacies, USP-grade
No charge until a provider approves
Live in South Dakota
8
protocols available today
Starting at
$161
per month, with free shipping + free doctor review
First shipment
5–7
business days after approval
Serving patients across South Dakota
Pepvio's telehealth platform serves patients in every corner of South Dakota, including:
And every other city, town, and ZIP code in South Dakota. If you're a South Dakota resident, you can use Pepvio.
How Pepvio works in South Dakota
Complete your intake
A 6-step medical assessment covering your goals, health history, contraindications, and current medications. Takes about 8 minutes.
Provider review
A South Dakota-licensed provider reviews your intake within 24 hours. If a protocol is appropriate, they'll prescribe one matched to your goals.
Delivered to South Dakota
Your prescription is filled by a 503A/503B compounding pharmacy and shipped directly to your South Dakota address — typically within 5-7 business days.
Protocols available in South Dakota
Peptide therapy and hormone optimization protocols, all available to South Dakota residents through our telehealth platform.
Peptides
Physician-guided peptide protocols, compounded by US pharmacies and delivered monthly.
Sermorelin
The most-prescribed peptide in longevity practice. A nightly injection that nudges your body's natural overnight rhythm: better sleep first, then faster recovery, then a leaner build over a few months.
$299/month
View protocol
PT-141 for Men
The ED peptide that works on the brain's arousal pathway, a different mechanism than the blood-flow medications. PT-141 (bremelanotide) supports both arousal and erection, taken as a small at-home injection on-demand before intimacy. Prescribed online by US-licensed physicians.
$299/month
View protocolLongevity
Evidence-backed healthspan protocols — the longevity molecules the research community has publicly committed to, dosed correctly and monitored properly.
NAD+ Longevity Protocol
Your body's natural energy supply, and the one that fades the most with age. Topping it back up is the foundational longevity protocol. Same intervention IV clinics charge per session for, taken at home as a nasal spray or a small self-administered injection.
$199/month
View protocol
Longevity Bundle
NAD+ and glutathione together: the two prescriptions most longevity clinicians reach for first. NAD+ for energy and DNA repair, glutathione for cellular cleanup. One subscription instead of two.
$499/month
View protocol
Glutathione Foundation
Your body's built-in cellular cleanup, the system that handles day-to-day cellular damage. Levels drop with age, alcohol, and chronic stress, and topping them back up has been part of compounded longevity practice for decades.
$209/month
View protocol
Methylene Blue Cognitive Protocol
In medicine since 1891, getting fresh attention from longevity circles. At low doses, it helps brain cells produce energy more efficiently, which matters most for focus and mental clarity. One capsule a day.
$299/month
View protocolWomen's Optimization
Bioidentical HRT for perimenopause and menopause — estradiol, progesterone, and topical formulations — plus PT-141 (the only FDA-approved peptide for female desire) in spray and injectable forms. Bundle option pairs both at a discount.
HRT
Bioidentical hormone replacement therapy for perimenopause and menopause. At your online visit, a US-licensed physician routes you to the components that fit: estradiol patches at your dose, progesterone, topical estradiol for local symptoms. You pick your bundle at checkout. Current-guideline HRT, prescribed online.
$199/month
View protocol
PT-141 for Women
The only FDA-approved peptide for female desire. PT-141 (bremelanotide) works on a brain pathway tied to arousal, a different mechanism than HRT. It comes in two forms, a nasal spray or a small at-home injection, both used as needed before intimacy.
$161/month
View protocolFrequently asked questions for South Dakota patients
Is peptide therapy legal in South Dakota?
Yes. Compounded peptides are legal in South Dakota when prescribed by a licensed physician and dispensed by a 503A or 503B compounding pharmacy. The FDA's Pharmacy Compounding Advisory Committee is scheduled to meet July 23-24, 2026 to consider reclassifying additional Category 2 peptides (BPC-157, KPV, TB-500, MOTS-C) back to Category 1, which would restore broader compounding access if the recommendations are adopted. Read the full breakdown.
Do I need to visit a clinic in South Dakota?
No. Pepvio operates entirely via telehealth. You complete your medical intake online, a licensed provider reviews it remotely, and your prescription is shipped directly to you — whether you're in Sioux Falls, Rapid City, or anywhere else in South Dakota.
How much do Pepvio protocols cost in South Dakota?
Pepvio's live protocols range from $161 to $499 per month. The doctor review and shipping are free, so you only pay for the compounded medication from a licensed pharmacy. No clinic fees or hidden charges. See our full cost breakdown.
How fast is delivery to South Dakota?
Most South Dakota patients receive their first shipment within 5-7 business days after their prescription is approved by a provider. Refills ship automatically each month so you never run out.
What protocols are available?
Available today: NAD+ Longevity Protocol, Sermorelin, Longevity Bundle, Glutathione Foundation, Methylene Blue Cognitive Protocol, HRT, PT-141 for Women, PT-141 for Men.
Ready to start in South Dakota?
Take our 8-minute health assessment to see which protocol matches your goals. No commitment — and no charge until a South Dakota-licensed provider approves.