More energy. Sharper mind. Faster recovery.
The injectable form of NAD+ — your body's natural energy supply, which fades with age. Prescription, reviewed online by a US-licensed physician.
- Real prescription NAD+ — not a supplement
- All-inclusive: provider, medication, and shipping in one price
- Compounded for each prescription by a US licensed pharmacy
Less than $10 a day
$299 billed monthly·all-inclusive: provider, medication, shipping
2 minutes · No commitment until a provider approves
~50%
Less NAD+ by midlife
1906
NAD+ first discovered
24 hours
Physician review
Licensed providers in your state
503A/B pharmacies, USP-grade compounding
No charge until a provider approves
- Cancel, pause, or switch protocols anytime — no annual commitment.
- All-inclusive pricing — provider, medication, and shipping in one monthly number. No surprise bills.
- Ongoing provider access — message your prescriber anytime through the patient portal.
Energy not what it used to be — and the usual fixes haven't moved it
Already tried NMN/NR oral supplements and want something more direct
Researching the IV-clinic protocol as a subscription alternative
Real prescription NAD+ — not a supplement
All-inclusive: provider, medication, and shipping in one price
Compounded for each prescription by a US licensed pharmacy
It's not just aging.
Adults' NAD+ levels drop by roughly half by age 50. The energy your body needs to function fades with it. That's why energy drops, mental clarity gets harder to hold, and recovery slows — even when sleep and nutrition haven't changed. Injectable NAD+ replaces what you've lost — directly, without your gut breaking it down.
What NAD+ actually does in your cells
Four jobs NAD+ has to keep up with — and why levels matter as you age.
Cellular energy
Your cells need NAD+ to turn food into ATP, the fuel they actually run on. No NAD+, no energy.
DNA repair
The enzymes that patch up day-to-day DNA damage burn through NAD+ doing it. Less NAD+, slower repair.
Sirtuins
Sirtuins are a family of cellular-housekeeping enzymes studied heavily in longevity research. They run on NAD+.
Falls sharply with age
By 50, levels are roughly half of what they were at 20 — and the slide continues. Topping them back up is the whole idea.
NAD+ levels decline sharply with age
Skin-cell NAD+ measured by mass spectrometry across age groups.
Source: Massudi et al. Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue. PLOS ONE, 2012.
What the research says
Three peer-reviewed studies on NAD+ in human and mammalian longevity.
Age-associated changes in oxidative stress and NAD+ metabolism in human tissue
Massudi et al., 2012
Cellular NAD+ levels in human skin fall by ~50% between age 20 and age 50, with continued decline thereafter.
DOI: 10.1371/journal.pone.0042357NAD+ intermediates: the biology and therapeutic potential of NMN and NR
Yoshino et al., 2018
NAD+ precursors NMN and NR demonstrate efficacy in restoring cellular NAD+ levels and improving metabolic markers in mammalian models.
DOI: 10.1016/j.cmet.2017.11.002Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Martens et al., 2018
Daily NAD+ precursor supplementation in adults aged 55–79 sustainably elevated whole-blood NAD+ levels with no significant adverse events.
DOI: 10.1038/s41467-018-03421-7What people have been trying — and where injectable NAD+ fits
| Injectable NAD+ | Oral NMN/NR supplements | Nothing | |
|---|---|---|---|
| Bypasses gut breakdown | ✓ Yes — direct to bloodstream | No — degraded in the gut | — |
| Prescribed by US physicians | ✓ Yes | No — over-the-counter | — |
| Compounded by US pharmacies | ✓ Yes — pharmaceutical-grade | No — supplement-grade | — |
| Effects in weeks vs months | ✓ 2–4 weeks for energy + clarity | Less reliable, often months | — |
What happens after you click
- Step 1
Today
2-minute online visit. No charge unless a physician approves.
- Step 2
Within 24 hours
A US-licensed physician reviews your intake and approves a protocol that fits — or tells you it isn't right for you.
- Step 3
5–7 days
Your prescription arrives in discreet packaging from a licensed US pharmacy.
What's in this protocol
NAD+
100-300mg weekly or biweekly, subcutaneous injection
Your body's natural energy supply at the cellular level. Levels drop roughly in half between age 20 and 50 — and keep fading. Topping it back up is the foundational longevity intervention clinicians have been doing for years, now in a once- or twice-weekly home injection instead of an IV-clinic visit.
Flexible payment options available at checkout · Cancel anytime
Inside your kit
- 1
NAD+ injection vial
Compounded by a licensed pharmacy in your state.
- 2
Sterile syringes
Sized for subcutaneous self-administration.
- 3
Alcohol swabs
Single-use, individually sealed.
- 4
Sharps disposal container
FDA-cleared, included with first shipment.
- 5
Dosing instructions
Provider-personalized dosing schedule.
Reviewed and prescribed by a US-licensed physician
Every Pepvio prescription is reviewed by a US-licensed physician. Real intake review, real prescription decision, real follow-up adjustments. We're not a supplement company. Your physician decides if NAD+ is right for you based on your intake — and if it isn't, you aren't charged.
Ready to start?
Take a free 2-minute assessment. If a licensed provider approves your protocol, your medication ships directly to your door. Not approved? Your card is never charged.
See if I qualifyPepvio protocols require a valid prescription from a licensed healthcare provider. All medications are compounded by licensed pharmacies. Pepvio does not provide medical advice; all medical decisions are made by licensed providers in our network. Individual results may vary.