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Longevity protocol

The antioxidant your body makes less of with age.

Glutathione is the cellular cleanup system your body makes itself. Levels drop with age, alcohol, chronic stress, and toxin exposure, and topping them back up has been part of compounded longevity practice for decades.

  • Real prescription glutathione, not an oral supplement
  • Pairs naturally with NAD+ (bundled Longevity Stack saves $99)
  • Compounded for each prescription by a US licensed pharmacy

From less than $4 a day

on a six-month plan

$150/mo$120/mo20% offyour first 6 months

Discount applied automatically at checkout, no code to enter.

free shipping + free doctor review

HSA/FSA Eligible
See if I qualify

2 minutes · No commitment until a provider approves

Glutathione Foundation kit photograph
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1 in 5
describe sleep, fatigue, or brain fog

In 19,000 public comments we studied, nearly 1 in 5 women discussing menopause described broken sleep, fatigue, or brain fog. This protocol exists for the symptoms women actually talk about.

From the Pepvio Listening Study, Edition 1 · August 2026
  • Cancel, pause, or switch protocols anytime, no annual commitment.
  • Free doctor review and free shipping: you only pay for the medication, one monthly number with no surprise bills.
  • Ongoing provider access: message your prescriber anytime through the patient portal.
Sound familiar?
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Bouncing back from stress, alcohol, or training takes longer than it used to

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Already on NAD+ and want to layer protocols

?

Want a foundational antioxidant beyond OTC supplements

What this protocol does

Real prescription glutathione, not an oral supplement

Pairs naturally with NAD+ (bundled Longevity Stack saves $99)

Compounded for each prescription by a US licensed pharmacy

What glutathione actually does

Glutathione is the cleanup molecule your body makes itself. Levels drop with age, alcohol, and chronic stress.

Antioxidant cleanup

Mops up the day-to-day cellular damage that builds up just from being alive.

Liver support

Tags toxins so the liver can process them out — central to how detox actually works.

Immune function

Immune cells need glutathione to do their job — multiplying and responding to threats.

Drops with age

Older adults make less of it. Replenishing brings levels back up.

The science

Older adults make less glutathione

Sekhar et al. (2011) measured roughly 30% less glutathione production in adults around 75 vs. those around 25.

Source: Sekhar et al. American Journal of Clinical Nutrition, 2011.

~30% lower than age-25 baseline
60%70%80%90%100%2575Age (years)
The research

What the research says

Peer-reviewed work on glutathione decline and topping it back up.

American Journal of Clinical Nutrition

Deficient synthesis of glutathione underlies oxidative stress in aging

Sekhar et al., 2011

Adults 70+ make about 30% less glutathione than younger adults — and topping up the precursors brings it back.

DOI: 10.3945/ajcn.110.003483
Journal of Nutrition

Glutathione metabolism and its implications for health

Wu et al., 2004

A long review of glutathione's role as the body's main cellular antioxidant.

DOI: 10.1093/jn/134.3.489
Molecular Aspects of Medicine

Glutathione: overview of its protective roles, measurement, and biosynthesis

Forman et al., 2009

Lower glutathione tracks with several chronic-disease markers; restoring it tracks with better outcomes.

DOI: 10.1016/j.mam.2008.08.006

Two ways to take it. Pick what fits your life.

Nasal spray

A spray you take at home. The lower-cost way in.

  • No needles
  • Easy to travel with and keep on hand
  • The most affordable way to start
Pepvio glutathione nasal spray bottle

3 grams (3,000 mg) per bottle

200 mg/ml · 15 ml

From $120/mo your first 6 months

Best if you'd rather skip the needle.

At-home injection

A small subcutaneous injection, once or twice a week.

  • A precise dose, fully absorbed every time
  • The form compounded longevity practice has used for decades
  • Small subcutaneous injection, like an insulin pen
Pepvio medication vial

2 grams (2,000 mg) per vial

200 mg/ml · 10 ml

From $203.20/mo your first 6 months

Best if you want predictable dosing and absorption.

What's in this protocol

Glutathione

200mg subcutaneous injection, 1-2x weekly, or a nasal spray. Your provider sets your schedule.

Your body makes glutathione to mop up the day-to-day damage other cellular work creates. Levels drop with age, alcohol, chronic stress, and toxin exposure, and topping them back up has been part of compounded longevity practice for decades.

Starting from$150/mo$120/mofirst 6 months
HSA/FSA Eligible

Flexible payment options available at checkout · Cancel anytime · HSA/FSA reimbursable (Letter of Medical Necessity available from your provider on request)

Ready to start?

Take a free 2-minute assessment. If a licensed provider approves your protocol, your medication ships directly to your door. Not approved? Your card is never charged.

See if I qualify
Licensed providersHIPAA compliantNot charged if not approved

Pepvio protocols require a valid prescription from a licensed healthcare provider. All medications are compounded by licensed pharmacies. Pepvio does not provide medical advice; all medical decisions are made by licensed providers in our network. Individual results may vary.

$150/moFrom $120/mofirst 6 months
Free shipping + free doctor review
See if I qualify