Protocols

Every Pepvio protocol, in one place.

Peptide therapy and hormone optimization. All protocols are prescribed by licensed physicians and compounded by licensed pharmacies.

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Peptides

Peptide-anchored optimization protocols

Peptide therapies for deeper sleep, faster recovery, and a leaner build — prescribed online by a US-licensed physician.

Sermorelin

HSA/FSA Eligible

The most-prescribed peptide in longevity practice. A nightly injection that nudges your body's natural overnight rhythm: better sleep first, then faster recovery, then a leaner build over a few months.

From

$239

/mo, yearly plan

Sermorelin

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PT-141 for Men

HSA/FSA Eligible

The ED peptide that works on the brain's arousal pathway, a different mechanism than the blood-flow medications. PT-141 (bremelanotide) supports both arousal and erection, taken as a small at-home injection on-demand before intimacy. Prescribed online by US-licensed physicians.

From

$239

/mo, yearly plan

PT-141 (Bremelanotide)

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GLP-1 Weight Loss

Semaglutide and tirzepatide, prescribed online. Every price upfront, and it never rises with your dose.

From $129

/month

SemaglutideTirzepatide

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Longevity

Evidence-backed healthspan protocols

Longevity protocols for energy, cellular repair, and resilience to everyday damage — the ones longevity clinicians actually prescribe.

NAD+ Longevity Protocol

HSA/FSA Eligible

Your body's natural energy supply, and the one that fades the most with age. Topping it back up is the foundational longevity protocol. Same intervention IV clinics charge per session for, taken at home as a nasal spray or a small self-administered injection.

From

$199

/month

NAD+

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Longevity Bundle

HSA/FSA Eligible

NAD+ and glutathione together: the two prescriptions most longevity clinicians reach for first. NAD+ for energy and DNA repair, glutathione for cellular cleanup. One subscription instead of two.

From

$399

/mo, yearly plan

NAD+Glutathione

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Glutathione Foundation

HSA/FSA Eligible

Your body's built-in cellular cleanup, the system that handles day-to-day cellular damage. Levels drop with age, alcohol, and chronic stress, and topping them back up has been part of compounded longevity practice for decades.

From

$150

/mo, 6-month plan

Glutathione

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Methylene Blue Cognitive Protocol

HSA/FSA Eligible

In medicine since 1891, getting fresh attention from longevity circles. At low doses, it helps brain cells produce energy more efficiently, which matters most for focus and mental clarity. One capsule a day.

From

$269

/mo, quarterly plan

Methylene Blue

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Women's Optimization

Bioidentical HRT and FDA-approved sexual health protocols

For hot flashes, sleep disruption, and low desire — what clinicians actually prescribe for these symptoms.

HRT

HSA/FSA Eligible

Bioidentical hormone replacement therapy for perimenopause and menopause. At your online visit, a US-licensed physician routes you to the components that fit: estradiol patches at your dose, progesterone, topical estradiol for local symptoms. You pick your bundle at checkout. Current-guideline HRT, prescribed online.

From

$179

/mo, quarterly plan

EstradiolProgesteroneTopical Estrogen

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PT-141 for Women

HSA/FSA Eligible

The only FDA-approved peptide for female desire. PT-141 (bremelanotide) works on a brain pathway tied to arousal, a different mechanism than HRT. It comes in two forms, a nasal spray or a small at-home injection, both used as needed before intimacy.

From

$161

/month

PT-141 (Bremelanotide)

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Side by side

Compare live protocols

Quick reference for matching yourself to the right protocol. If you're not sure, our quiz will route you based on your goals and medical history.

HSA/FSA EligibleEvery protocol below can be paid for with your HSA or FSA card.

Protocol	Best for	Delivery	Labs	Price
NAD+ Longevity Protocol Longevity	Your body's natural energy supply, which fades with age. Same intervention IV clinics charge per session for, as a nasal spray or a small at-home injection.	Nasal spray or injection	Optional	From $199/mo
Sermorelin Peptides	A nightly injection that restores your body's natural overnight rhythm. Deeper sleep often shows up first, faster recovery next, leaner build over a few months.	Daily injection	Recommended	From $239/mo
Longevity Bundle Longevity	NAD+ for natural energy, glutathione for cellular cleanup. The two prescriptions longevity clinicians tend to reach for first.	At-home injections	Optional	From $399/mo
Glutathione Foundation Longevity	Your body's built-in cellular cleanup. Levels drop with age, alcohol, and chronic stress.	Nasal spray or injection	Optional	From $150/mo
Methylene Blue Cognitive Protocol Longevity	In medicine since 1891. Studied at low doses for memory and focus. One capsule a day.	Daily oral	Optional	From $269/mo
HRT Women’s Optimization	Bioidentical HRT, personalized at your online visit. For hot flashes, sleep, mood, and vaginal/genitourinary symptoms.	Picked at your online visit	Recommended	From $179/mo
PT-141 for Women Women’s Optimization	The only FDA-approved peptide for female desire (HSDD). Brain pathway, not hormones. Choose your form: nasal spray or small injection.	Nasal spray or injection	Optional	From $161/mo
PT-141 for Men Peptides	The ED peptide you've been looking for. Works on arousal, not just blood flow. A small, on-demand injection prescribed online.	At-home injection	Optional	From $239/mo
GLP-1 Weight Loss Peptides	Weight loss with semaglutide or tirzepatide. Every price upfront, and it never rises with your dose.	Weekly injection	Optional	From $129/mo

All protocols include a free physician review, ongoing provider messaging, and free shipping — you only pay for the medication. Bloodwork (when required or recommended) is run through your own primary care provider or a direct-to-consumer lab service — it's not included in the subscription. Flexible payment options available at checkout.

Not sure which protocol fits?

Take our 2-minute assessment. We'll match you to the protocol most aligned with your goals, and a licensed provider will confirm eligibility and prescribe the right dose. Not approved? Your card is never charged.

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2 minutes · No commitment · Licensed physician review · Flexible payment options

Pepvio protocols require a valid prescription from a licensed healthcare provider. All peptides are compounded by licensed pharmacies. Pepvio does not provide medical advice; all medical decisions are made by licensed providers in our network. Individual results may vary.